Matthew McMillin is an Assistant Professor of Biological Sciences, Neuroscience at Baylor College of Medicine. He received his Ph.D. in Neuroscience from Texas A&M University under the supervision of Dr. Sharon DeMorrow, where he investigated crosstalk between hedgehog and transforming growth factor beta signaling in liver injury, blood-brain barrier dysfunction and neuroinflammation. Dr. McMillin’s postdoctoral studies in the field of hepatology were performed under the mentorship of Drs. Gianfranco Alpini and Sharon DeMorrow. These studies investigated the role of neuropeptides and transforming growth factor beta signaling in liver pathology during toxin-induced acute liver failure and cholestatic liver diseases. After becoming faculty, Dr. McMillin’s research program has focused on the mechanisms leading to dysregulation, and subsequent recovery, of hepatic and neural physiology during acute liver failure and cholestatic liver diseases. Specifically, his program has been investigating the interaction between thrombospondin-1 and transforming growth factor beta 1 signaling in the context of hepatocyte necrosis, hepatic fibrosis, cellular senescence, blood-brain barrier function, neuroinflammation and neurological dysfunction. Outside of research, Dr. McMillin serves on the editorial board of neuroscience and hepatology journals including serving as an Associate Editor for Frontiers in Cellular Neuroscience.