Dr. Christopher Rose is currently Professor in the Department of Medicine at the Université de Montréal. He is director of the Hepato-Neuro laboratory which is located at University Hospital Research Center (CRCHUM). Dr. Rose received his PhD (Neuroscience/Biomedical Sciences) from the Université de Montréal in 2000.
He continued his research interests in Europe by pursuing post-doctoral studies in Germany (Prof. Kettenmann, Berlin), Spain (Prof. Felipo, Valencia and Prof. Cordoba, Barcelona) and Norway (Dr. Ytrebo, Tromso). In doing so, he was the recipient of 3 prestigious post-doctoral fellowship awards from the Alexander von Humboldt Foundation (Germany), Canadian Institute of Health Research (Canada) and the European Association for the Study of the Liver (Europe).
Dr. Rose’s research interests lie within the area of hepatic encephalopathy (HE), a field in which he has been researching for over 25 years. HE, a major neuropsychiatric complication of liver disease, touches close to 80% of patients with cirrhosis affecting their quality of life and resulting in significant socioeconomic burden, morbidity and mortality both pre and post-liver transplant. Translational research is the primary objective of Dr. Rose’s laboratory and, therefore, his research program is based on a bench-to-bedside concept.
Dr. Rose has a vested interest in deciphering the role of ammonia and the pathophysiological pathways involved in the development of cerebral complications associated with liver disease which ultimately will lead to novel therapeutic approaches, improving the management of patients with liver disease as well as neurological outcome post-liver transplantation. His research implicates both cellular models, animal models and patients.
Dr. Rose has the ability to mobilize his research and communicate his knowledge and findings to basic scientists, clinical scientists and treating physicians as well as to patients.
Dr. Rose is currently president elect for International Society for Hepatic Encephalopathy and Nitrogen Metabolism. He is chair of the Research Committee of the Canadian Association for the Study of the Liver and sits on the advisory board to the Institute of Nutrition, Metabolism and Disease of Canadian Institute of Health Research. In 2022, Dr. Rose received the Canadian Association for the Study of the Liver Distinctive Service Award as well as the Visiting Professor Award.
Dr. Rose has published over 95 scientific articles and over 65 students at all levels from throughout the world have trained in his laboratory.